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. 2014 Dec 16;9(12):e115009. doi: 10.1371/journal.pone.0115009

Figure 2. Experiment 1: Baseline locomotor activity in well habituated combined DAT/5-HT1B KO mice.

Figure 2

Total locomotor activity in DAT/5-HT1B KO mice (9 genotypes: DAT +/+5-HT1B +/+, DAT −/−5-HT1B +/+, DAT +/+5-HT1B −/−, DAT +/−5-HT1B −/−, DAT −/−5-HT1B +/−, DAT −/−5-HT1B −/−) expressed in terms of summed distance traveled during all of the 4 habituation sessions prior to drug (5, 10 and 20 mg/kg IP cocaine; C5, C10 and C20 respectively) or saline (SAL) injections. *Significant difference from DAT +/+5-HT1B +/+ mice based on Scheffe’s post hoc comparison (p<0.05). Data are represented as mean ± SEM.