Figure 3. Experiment 1: Cocaine-induced locomotion in well habituated DAT/5-HT1B KO mice.
Cocaine-induced locomotor activity in DAT/5-HT1B KO mice is expressed as absolute difference s from baseline, preinjection values. Post hoc analysis by 1 way ANOVA for COCAINE concentration revealed significant effects of cocaine for all genotypes except DAT −/−5-HT1B +/+ and DAT −/−5-HT1B −/−. Data are represented as mean ± SEM.