Figure 4. OptiBET workflow.
Visual representation of the optiBET script workflow: (1) initial approximate brain extraction is performed using BET (and options ‘B’ and ‘f’, as suggested previously [5]); (2) sequential application of a linear and non-linear transformation from native space to MNI template space; (3) back-projection of a standard brain-only mask from MNI to native space; and (4) mask-out brain extraction.