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. Author manuscript; available in PMC: 2016 Jan 1.
Published in final edited form as: Metabolism. 2014 Aug 15;64(1):24–34. doi: 10.1016/j.metabol.2014.08.004

Figure 2. The effects of leptin in glucose and lipid metabolism.

Figure 2

Leptin can affect glucose homeostasis through a variety of mechanisms, including modulation of ANS, hepatic glucose production, muscle glucose uptake, and glucagon secretion from pancreatic α-cells. Leptin inhibits insulin secretion, and stimulates fatty acid oxidation. Abbreviations: ANS, autonomic nervous system.