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. Author manuscript; available in PMC: 2015 Dec 30.
Published in final edited form as: Int J Pharm. 2014 Oct 22;477(0):334–343. doi: 10.1016/j.ijpharm.2014.10.022

Fig. 5.

Fig. 5

AR-12/MP-induced autophagosome formation in hMDMs is greater than or equal to free AR-12. (A) Nuclei were stained with DAPI (blue) and autophagosomes were labeled with a cationic amphiphilic tracer dye (green). The results shown are representative of two experiments. (B) Western blot using anti-LC3 antibody. LC3 cleavage was induced by AR-12/MPs; (1) Medium control; (2) Equivalent amount of blank MPs; (3) 1.25µM free AR-12; (4) 1.25 µM AR-12/MPs; (5) 100nM LPS and 100nM IFN-γ as a positive control. The results are representative of five experiments.