Figure 6.

A/J preferentially expresses the long isoform of Apobec1 in response to a high-fat, cholic acid diet. Apobec1 expression levels of the short (A) and long (B) isoforms from RNA from liver tissue from A/J and C57BL/6J founder strain mice. A/J mice on a high-fat, cholic acid diet exhibit increased expression of both the long and short transcripts of Apobec1 in a diet-dependent manner, *P > 0.05. Apobec1 levels for each sample were normalized relative to RPS20. Fold changes are reported as the relative expression in A/J vs. C57BL/6J samples. Data are presented as mean ± SD, and significance was determined using a Student’s t-test.