Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Oct 27;4(12):2483–2492. doi: 10.1534/g3.114.014712

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2014 Downes et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution Unported License (http://creativecommons.org/licenses/by/3.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

4-NQO induces all six possible base pair substitutions. Distribution of the number of substitutions affecting guanine-cytosine (A) and adenine-thymine (B) base pairs per mutant. Note the different scales on the x-axis for A and B. The dashed line in B shows the predicted number of spontaneous mutations per individual. Boxplots show minimum and maximum values within 1.5 × interquartile range of the box (whiskers), median (dividing line), mean (circle), 95% confidence interval of mean (diamond), and outliers (squares). Using unpaired unequal distribution Student’s t-test: NS, not significantly different, *P < 0.05 and ***P < 0.001.