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. Author manuscript; available in PMC: 2015 Dec 28.
Published in final edited form as: J Control Release. 2014 Oct 24;0:272–286. doi: 10.1016/j.jconrel.2014.10.016

Table 2.

Pharmacokinetic parameters of DOX in different formulations

t1/2 (h) AUC (μg/mL×h) CL (mL/h) Cmax (μg/mL) Vd (mL)
DOX 4.20±0.35 5.43±0.11 18.40±2.39 3.64 t0.30 25.32±2.15
PEG5K-VE2/DOX 14.89±2.08 70.58f±6.68 1.47±0.15 14.51±1.39 6.26±0.43
PEG5K-Fmoc-VE2/DOX 19.41±1.76 104.36±11.52 0.72±0.055 27.62±2.60 3.29±0.24