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. Author manuscript; available in PMC: 2015 Jun 11.
Published in final edited form as: Nature. 2014 Sep 28;516(7530):246–249. doi: 10.1038/nature13788

Figure 1. Changes in diet limit the development of inflammatory bone disease in Pstpip2cmo mutant mice.

Figure 1

a-d, Wild-type (WT) and Pstpip2cmo mutant mice were fed a lean fat diet (LFD) or a high fat and cholesterol diet (HFD). a, Incidence of inflammatory bone disease. b-d, Representative isosurface micro-CT paw scans (b), H&E sections (c) and pathology scores (d) for hind paw samples from 12-14 week old WT, LFD Pstpip2cmo and HFD Pstpip2cmo mice. Each point represents an individual mouse, and the line represents the mean ± s.e.m. (***P < 0.001; Student’s t-test)