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. Author manuscript; available in PMC: 2015 Dec 15.
Published in final edited form as: Cancer Res. 2014 Nov 6;74(24):7371–7382. doi: 10.1158/0008-5472.CAN-14-0794

Figure 6.

Figure 6

MAPK/ERK signaling is critical for endometrial cancer progression and development. (A) Immunohistochemical analysis of phospho-ERK1/2 in the uteri of Ptend/d mice treated with vehicle (a) and U0126 (b). (B) Ptend/d mice treated with U0126 shows decreased uterine weight compared with Ptend/d mice treated with vehicle. The results represent the mean ± SEM. *** p<0.001, ** p<0.01. (C) Gross morphology of Ptend/d mice treated with vehicle (a) and U0126 (b). (D) Hematoxylin-eosin staining of Ptend/d mice treated with vehicle (a and c) and U0126 (b and d).