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. Author manuscript; available in PMC: 2015 Jul 1.
Published in final edited form as: Pediatr Res. 2014 Oct 3;77(0):64–69. doi: 10.1038/pr.2014.145

Figure 1.

Figure 1

Inhibition of ENaC results in the progression of cyst formation in PCK rats. (a) Morphology of the kidneys collected from PCK rats after 4 or 12 weeks treatment with benzamil (benza) or vehicle (control). Scale bar is 5 mm. (b) Kidney weight/total body weight (TBW) ratios were calculated and graphed as a percentage. (c) Cysts area, % of total slice. Kidney sections were morphometrically analyzed as described in Materials and Methods to determine the surface area of the remaining kidney tissue relative to the cyst space. N = 6 rats in each group. *p<0.05 vs vehicle-control.