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. Author manuscript; available in PMC: 2015 Jul 1.
Published in final edited form as: Pediatr Res. 2014 Oct 3;77(0):64–69. doi: 10.1038/pr.2014.145

Figure 5.

Figure 5

ENaC activity in cystic and non-dilated tubules. (a) Representative current traces for ENaC activity measured in cell attached patches in freshly isolated non-cystic CDs and cysts of 16 week old SD or PCK rats. These patches were held at a test potential of Vh = –Vp = −40 mV. Inward Li+ currents are downward. Dashed lines indicate the respective current state with a “c” and “on” denoting the closed and open states. (b) Summary graph of observed ENaC activity (NPo). N = 6–8, recorded from 3–4 tubules or cysts isolated from different rats per group; number of patches acquired from an animal was 1–4. *P<0.05 versus PCK tubules; † P<0.05 versus SD tubules.