Table 1.
Overall Characteristics of the MESA Cohort
| Descriptive Characteristics | Overall n= 4145 | Men n=2001 | Women n=2144 | P-Value |
|---|---|---|---|---|
| Age (years), mean (SD) | 61.3 (10.1) | 61.3 (10.1) | 61.3 (10.1) | 1.00 |
| Height (cm), mean (SD) | 166.4 (10.0) | 173.4 (7.7) | 160.0 (7.1) | <0.001 |
| Weight (kg), mean (SD) | 76.9 (16.1) | 82.4 (14.6) | 71.8 (15.7) | <0.001 |
| Diabetes, n (%) | 489 (12%) | 263 (13%) | 226 (11%) | 0.009 |
| Hypertension, n (%) | 1739 (42%) | 803 (40%) | 936 (44%) | 0.02 |
| Current Smoker, n (%) | 1466 (35%) | 861 (43%) | 605 (28%) | <0.001 |
| Race | ||||
| White, n (%) | 1569 (38%) | 754 (38%) | 815 (38%) | 0.83 |
| Black, n (%) | 1019 (25%) | 462 (23%) | 557 (26%) | 0.03 |
| Chinese, n (%) | 571 (14%) | 287 (14%) | 284 (13%) | 0.31 |
| Hispanic, n (%) | 986 (24%) | 498 (25%) | 488 (23%) | 0.11 |
| Urine Albumin:Creatinine Ratio (mg/g); median (25%, 75%) | 5.18 (3.3, 10.2) | 4.7 (3.0, 9.7) | 5.59 (3.6, 10.7) | 0.06 |
| Estimated GFR (mL/min/1.73 m2), mean (SD) | 78.5 (15.7) | 78.9 (15.6) | 78.2 (15.9) | 0.15 |
| Total Cholesterol (mg/dL), mean (SD) | 194.4 (35.2) | 188.6 (34.0) | 199.8 (35.5) | <0.001 |
| LDL (mg/dL), mean (SD) | 117.2 (31.2) | 117.2 (30.9) | 117.3 (31.5) | 0.89 |
| HDL (mg/dL), mean (SD) | 51.1 (14.9) | 45.1 (11.6) | 56.7 (15.4) | <0.001 |
| Triglycerides (mg/dL), mean (SD) | 131.9 (82.7) | 135.2 (88.6) | 128.9 (76.6) | 0.01 |
| Statin Use, n (%) | 595 (14.3%) | 272 (13.6%) | 323 (15%) | 0.17 |
| Systolic Blood Pressure, mean (SD) | 134.0 (20.5) | 133.7 (19.1) | 134.2 (21.7) | 0.38 |
| Diastolic Blood Pressure, mean (SD) | 77.4 (11.0) | 80.0 (10.3) | 75.0 (11.1) | <0.001 |
| Mean Arterial Pressure, mean (SD) | 100.8 (14.0) | 101.6 (13.0) | 100.0 (14.8) | <0.001 |
| Antihypertensive Medication Use, n (%) | 1428 (34%) | 653 (33%) | 775 (36%) | 0.02 |
| LV Mass (grams), mean (SD) | 145.5 (38.6) | 168.5 (35.9) | 123.9 (26.8) | <0.001 |
| LV Mass indexed to BSA (g/m2), mean (SD) | 78.1 (15.6) | 85.7 (15.4) | 70.9 (12.1) | <0.001 |
| Percent Predicted LV mass (%), mean (SD) | 103.9 (17.9) | 103.2 (18.3) | 104.5 (17.5) | 0.02 |
| LV Wall Volume to Cavity Volume Ratio, mean (SD) | 1.11 (0.21) | 1.16 (0.22) | 1.06 (0.19) | <0.001 |