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. Author manuscript; available in PMC: 2015 Sep 10.
Published in final edited form as: Int J Pharm. 2014 Jun 27;472(0):356–361. doi: 10.1016/j.ijpharm.2014.06.044

Table 2.

Minimum inhibitory concentration (MIC) values of APs measured using bacterial and microbial organisms (Lucchini et al. 1990, Simpson and Wuthiekanun 2000, Meyer et al. 2007, Rowe et al. 2009, Abd-Elsalam et al. 2011).

Preservative and Typical Use Concentration Typical Use Concentration [μg/ml] Organism Tested MIC [μg/ml]
Benzyl Alcohol, 1% vol/vol 10400 Aspergillus niger
Candida albicans
Escherichia coli
Pseudomonas aeruginosa
Staphylococcus aureus
5000
2500
2000
2000
25
m-Cresol, 0.3% vol/vol 3090 Aspergillus niger
Bacillus subtilis
Burkholderia pseudomallei
Candida albicans
Pseudomonas aeruginosa
Staphylococcus aureus
2000
1000
125
2500
1000
1000
Phenol, 0.5% vol/vol 5350 Aspergillus niger
Bacillus aerogenes
Enterococcus faecium
Escherichia coli
Pseudomonas aeruginosa
Staphylococcus aureus
311
697
3600
2500
1800
1800
Phenoxyethanol, 1% vol/vol 11000 Aspergillus niger
Candida albicans
Escherichia coli
Pseudomonas aeruginosa
Staphylococcus aureus
3300
5400
3600
3200
8500