RSVA405 and RSVA314 decrease apoptosis after renal I/R. Kidney tissues of the vehicle-, RSVA405- and RSVA314-treated rats were collected 24 h after reperfusion. (A) Representative photomicrographs of terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL; green) and 4′,6-diamidino-2-phenylindole (DAPI) as counterstain (blue) at 200× magnification. (B) Graph representing the number of TUNEL positive nuclei per high power field as described in Materials and Methods. Data are presented as mean ± standard error (n=3–4/group). *P < 0.05 vs. control; #P < 0.05 vs. vehicle. Con, control; Veh, vehicle; R405, RSVA405; and R314, RSVA314.