Skip to main content
. Author manuscript; available in PMC: 2016 Jan 1.
Published in final edited form as: Hypertension. 2014 Oct 13;65(1):130–139. doi: 10.1161/HYPERTENSIONAHA.114.04473

Figure 3.

Figure 3

(A) EDH-mediated responses in the presence of the selective IK1 channel blocker TRAM-34 in MAs derived from wt (circles), Trx-Tg (upward triangles) and dnTrx-Tg (downward triangles) mice. Insert: Percentage inhibition of the EDH response by TRAM-34 in MAs derived from wt (white bars), Trx-Tg (blue bars) and dnTrx-Tg (red bars) mice. (B) EDH-mediated responses in the presence of the selective SK3 channel blocker UCL-1684 in MAs derived from wt (circles), Trx-Tg (upward triangles) and dnTrx-Tg (downward triangles) mice. Insert: Percentage inhibition of the EDH response by UCL-1684 in MAs derived from wt (white bars), Trx-Tg (blue bars) and dnTrx-Tg (red bars) mice. (C) EDH-mediated responses in the combined presence of TRAM-34 and UCL-1684 in MAs derived from wt (circles), Trx-Tg (upward triangles) and dnTrx-Tg (downward triangles) mice. Values are means ± SEM (n=6-8 mice). * P< 0.05 Trx-Tg compared with wt or dnTrx-Tg.