Table A1.
Demographic and Clinical Characteristics of Patients With Pancreatic Cancer by Diabetes Status at Diagnosis
| Characteristic | NHS and HPFS |
DFCI |
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| No Diabetes (n = 825) |
Short Term (≤ 4 years; n = 47) |
Long Term (> 4 years; n = 134) |
No Diabetes (n = 265) |
Short Term (≤ 4 years; n = 72) |
Long Term (> 4 years; n = 49) |
|||||||
| No. | % | No. | % | No. | % | No. | % | No. | % | No. | % | |
| Age at diagnosis, years | ||||||||||||
| Mean | 70.8 | 71.9 | 74.6 | 63.2 | 65.0 | 68.0 | ||||||
| SD | 8.4 | 7.9 | 7.0 | 11.2 | 10.1 | 9.1 | ||||||
| Female sex | 520 | 63.0 | 33 | 70.2 | 82 | 61.2 | 138 | 52.1 | 29 | 40.3 | 17 | 34.7 |
| Race/ethnicity | ||||||||||||
| White | 781 | 94.7 | 46 | 97.9 | 127 | 94.8 | 248 | 93.6 | 65 | 90.3 | 46 | 93.9 |
| Black | 13 | 1.6 | 0 | 0.0 | 1 | 0.7 | 2 | 0.8 | 2 | 2.8 | 0 | 0.0 |
| Other | 16 | 1.9 | 0 | 0.0 | 4 | 3.0 | 4 | 1.5 | 1 | 1.4 | 1 | 2.0 |
| Unknown | 15 | 1.8 | 1 | 2.1 | 2 | 1.5 | 11 | 4.2 | 4 | 5.6 | 2 | 4.1 |
| BMI, kg/m2 | ||||||||||||
| Mean | 25.7 | 27.3 | 28.1 | 28.4 | 30.8 | 31.8 | ||||||
| SD | 4.6 | 5.3 | 5.5 | 7.8 | 5.7 | 7.5 | ||||||
| Physical activity, MET-hr/wk | ||||||||||||
| Mean | 22.8 | 23.3 | 16.6 | 15.7 | 8.4 | 11.5 | ||||||
| SD | 27.9 | 33.3 | 25.1 | 27.1 | 13.3 | 22.4 | ||||||
| Smoking status | ||||||||||||
| Never | 330 | 40.0 | 20 | 42.6 | 52 | 38.8 | 93 | 35.1 | 22 | 30.6 | 16 | 32.7 |
| Past | 367 | 44.5 | 22 | 46.8 | 58 | 43.3 | 117 | 44.2 | 35 | 48.6 | 25 | 51.0 |
| Current | 108 | 13.1 | 5 | 10.6 | 24 | 17.9 | 24 | 9.1 | 9 | 12.5 | 4 | 8.2 |
| Missing | 20 | 2.4 | 0 | 0.0 | 0 | 0.0 | 31 | 11.7 | 6 | 8.3 | 4 | 8.2 |
| Cancer stage | ||||||||||||
| Localized | 127 | 15.4 | 7 | 14.9 | 15 | 11.2 | 46 | 17.4 | 6 | 8.3 | 7 | 14.3 |
| Locally advanced | 100 | 12.1 | 7 | 14.9 | 9 | 6.7 | 43 | 16.2 | 20 | 27.8 | 6 | 12.2 |
| Metastatic | 380 | 46.1 | 21 | 44.7 | 79 | 59.0 | 176 | 66.4 | 46 | 63.9 | 36 | 73.5 |
| Unknown | 218 | 26.4 | 12 | 25.5 | 31 | 23.1 | 0 | 0.0 | 0 | 0.0 | 0 | 0.0 |
| Diagnosis period | ||||||||||||
| 1986-2000 | 437 | 53.0 | 23 | 48.9 | 48 | 35.8 | 0 | 0.0 | 0 | 0.0 | 0 | 0.0 |
| 2001-2013 | 388 | 47.0 | 24 | 51.1 | 86 | 64.2 | 265 | 100.0 | 72 | 100.0 | 49 | 100.0 |
Abbreviations: BMI, body-mass index; DFCI, Dana-Farber Cancer Institute; HPFS, Health Professionals Follow-Up Study; MET, metabolic equivalent; NHS, Nurses' Health Study; SD, standard deviation.