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. 2014 Oct 20;33(1):42–50. doi: 10.1200/JCO.2014.56.8253

Table A1.

Initial Radioiodine Treatment Doses by BRAF V600E Mutation Status in PTC (all types)

Location No. of Patients BRAF Mutation Positive
BRAF Mutation Negative
P*
Median IQR Median IQR
Medical Center
Johns Hopkins Hospital 387 76 0 to 100 30 0 to 100 .03
University of Pittsburgh 162 135 106 to 161 105 0 to 134 < .001
Memorial Sloan-Kettering Cancer Center 90 104 30 to 197 75 0 to 150 .05
Yale University 17 158 51 to 243 100 0 to 209 .38
University of Pisa 189 30 30 to 30 30 30 to 30 .60
University of Perugia 117 100 50 to 100 100 50 to 100 .37
University of Milan 110 80 50 to 80 50 0 to 80 .07
University of Padua 135 100 100 to 150 100 100 to 150 .57
University of Bologna 32 100 50 to 100 100 98 to 100 .86
Kanagawa Cancer Center 49 0 0 to 0 0 0 to 0 1.0
Maria Sklodowska-Curie Memorial Cancer Centre and Institute of Oncology 98 100 100 to 100 100 100 to 100 .84
Griffith Medical School 0
University of Sydney 84 143 108 to 162 162 135 to 270 .26
Hospital La Paz Health Research Institute 66 120 100 to 150 100 100 to 150 .13
Institute of Endocrinology, Prague 221 100 0 to 102 100 0 to 119 .93
University of Ulsan 197 150 150 to 150 150 150 to 150 .008
Country
United States 656 100 0 to 140 53 0 to 103 < .001
Italy 583 100 30 to 100 50 30 to 100 < .001
Japan 49 0 0 to 0 0 0 to 0 1.0
Poland 98 100 100 to 100 100 100 to 100 .84
Australia 84 143 108 to 162 162 135 to 270 .26
Spain 66 120 100 to 150 100 100 to 150 .13
Czech Republic 221 100 0 to 102 100 0 to 119 .93
South Korea 197 150 150 to 150 150 150 to 150 .008
Overall 1954 100 50 to 150 100 27 to 103 < .001

Abbreviations: IQR, interquartile range; PTC, papillary thyroid cancer.

*

P value from Wilcoxon signed-rank test.