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. Author manuscript; available in PMC: 2016 Jan 1.
Published in final edited form as: Bone. 2014 Aug 28;70:62–65. doi: 10.1016/j.bone.2014.07.026

Figure 1.

Figure 1

LLP2A-Ale is a hybrid compound. It is composed of the bisphosphonate, alendronate, that has high affinity for the bone tissue. The alendronate is bound to a chemical linker that also is attached to LLP2A, a synthetic protein that has high affinity for alpha 4, beta 1 integrin that is on the surface of Mesenchymal stem cells and hematopoetic stem cells.