Table 1.
Studies that assessed the potential association between deep venous thrombosis and common risk factors of atherosclerosis
| Ref. | Study design | Study population | Number | Findings |
|---|---|---|---|---|
| Rumley A (5) Heit JA (6) |
Prospective cohort Population-base |
Men aged 60-79 | 3861 | Age, risk factor for atherosclerosis is risk factor for DVT |
| Jezovnik MK (7) Kyrle PA (8) |
Case-control | Idiopathic DVT Healthy controls DVT |
47 44 |
Higher recurrence of idiopathic DVT in men versus women |
| Hansson PO (9) | Prospective cohort | Men aged > 50 | 855 | Waist circumference and smoking are risk factors for DVT |
| Goldhaber SZ (10) Stein PD (11) Glynn RJ (12) |
Prospective cohort Population-base Prospective cohort |
Women aged 30-55 | 112822 | Obesity, hypertension and smoking are risk factors for DVT |
| Petrauskiene V (13) Hong C (14) |
Case-control Case-control |
Patients with diabetes Control without diabetes Idiopathic DVT Healthy controls |
56 246 89 89 |
Diabetes is risk factor for DVT Diabetes and hypertension are risk factors for DVT |
| Deguchi H (15) Doggen CJ (16) Vaya (17) |
Case-control Case-control Case-control |
Males < 55 with DVT Age-matched controls Postmenopausal women with a first venous thrombosis Postmenopausal women Patients with DVT Healthy controls |
49 49 477 1986 143 194 |
Low HDL and high LDL cholesterol are risk factors for DVT Triglycerides are a risk factor for DVT Hypercholesterolemia and obesity are risk factors for DVT |
| Marcucci R (18) Vormittag R (19) |
Case-control Case-control |
Patients with DVT Healthy controls Patients with DVT Healthy controls |
603 430 128 122 |
Lipoprotein(a) is a risk factor for DVT No association between lipoprotein(a) and DVT |
| Ageno W (20) Ay C (21) |
Case-control | Patients with DVT Healthy controls Patients with DVT Healthy controls |
97 103 116 129 |
Metabolic syndrome is a risk factor for DVT |
| Tsai AW (22) | Prospective cohort | Subject >45 | 19293 | Diabetes and obesity, but not hypertension, hyperlipaemia or smoking risk factors of DVT |
| Glynn RJ (23) | Prospective cohort | Male physicians | 18662 | Obesity, but not hypertension, hypercholesterolaemia, diabetes or smoking risk factors of DVT |
| Sigrid K (24) | Population-base | Subject >25 | 27158 | Smoking, hypertension, dyslipidemia and diabetes are not risk factors of DVT |
DVT: deep venous thrombosis; HDL: high-density lipoproteins; LDL: low-density lipoproteins