Table 2.
Association between ACR Criteria and Anti-Clq in SLE: Percentage of Patients with Various Clinical Conditions, by Anti-C1q Status
| ACR Criteria | Anti-C1q Positive (%) | Anti-C1q Negative (%) | p-value | Odds Ratio (95% CI) | Adjusted p-value for Age |
|---|---|---|---|---|---|
| Malar Rash | 47.7 | 46.9 | 0.90 | 0.9 (0.5, 1.5) | 0.69 |
| Discoid Rash | 19.8 | 19.4 | 0.94 | 1.1 (0.6, 2.1) | 0.71 |
| Photosensitivity | 53.5 | 53.2 | 0.96 | 1.0 (0.6, 1.7) | 1.00 |
| Oral Ulcers | 38.4 | 46.4 | 0.20 | 0.7 (0.4, 1.1) | 0.14 |
| Arthritis | 64.0 | 65.8 | 0.76 | 0.9 (0.5, 1.5) | 0.70 |
| Serositis | 37.2 | 34.7 | 0.68 | 1.1 (0.6, 1.8) | 0.84 |
| Pleurisy | 31.4 | 28.4 | 0.60 | 1.1 (0.6, 1.9) | 0.74 |
| Pericarditis | 14.0 | 12.2 | 0.67 | 1.2 (0.6, 2.5) | 0.66 |
| Proteinuria | 50.0 | 22.5 | <0.01 | 3.0 (1.7, 5.1) | <0.01 |
| Red cell casts | 18.6 | 7.2 | <0.01 | 2.6 (1.2, 5.4) | 0.02 |
| Seizure | 5.8 | 4.1 | 0.51 | 1.2 (0.4, 3.8) | 0.72 |
| Psychosis | 3.5 | 0.5 | 0.04 | 9.5 (0.9, 98.5) | 0.06 |
| Hematologic | 64.0 | 58.1 | 0.35 | 1.2 (0.7, 2.0) | 0.49 |
| Leukopenia | 40.7 | 35.1 | 0.36 | 1.2 (0.7, 2.0) | 0.48 |
| Lymphopenia | 38.4 | 36.5 | 0.76 | 1.1 (0.7, 1.8) | 0.73 |
| Thrombocytopenia | 15.1 | 12.2 | 0.49 | 1.1 (0.5, 2.2) | 0.86 |
| Anti-dsDNA | 77.9 | 47.8 | <0.01 | 3.4 (1.9, 6.1) | <0.01 |
| Anti-Smith | 33.7 | 14.4 | <0.01 | 2.8 (1.5, 5.0) | 0.01 |
| Antiphospholipid | 57.0 | 54.5 | 0.70 | 1.1 (0.7, 1.8) | 0.70 |