Table 4.
Odds ratios (OR) of SLICC renal involvement a in patients with SLE (N=308) by individual antibody status, adjusted for demographic and serologic characteristics
| Covariates | SLICC renal (OR) | 95% CI | p-value |
|---|---|---|---|
| Age (years) | |||
| ≤30 (ref.)b | 1.00 | ||
| >30 | 0.44 | 0.25 – 0.78 | <0.01 |
| Ethnicity | |||
| African American (ref.) | 1.00 | ||
| White | 0.28 | 0.14 – 0.60 | <0.01 |
| Asian | 0.42 | 0.16 – 1.08 | 0.07 |
| Hispanic/Latino | 0.40 | 0.09 – 1.71 | 0.22 |
| Gender | |||
| Male (ref.) | 1.00 | ||
| Female | 0.46 | 0.19 – 1.14 | 0.09 |
| ANA | 0.22 | 0.05 – 1.01 | 0.05 |
| Anti-dsDNA | 4.05 | 2.10 – 7.90 | <0.01 |
| Low Complement | 1.87 | 0.98 – 3.59 | 0.06 |
| Anti-Clq | 2.30 | 1.26 – 4.19 | <0.01 |
a
SLICC renal involvement is defined as urine protein-to-creatinine ratio (or 24-hour urine protein) representing 500mg/24 hours or red blood cell casts; estimates from multivariable logistic regression model, constant term 3.44, 95% CI 0.51 – 23.07, p-value 0.2)
b
ref. denotes the reference group for each category