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. Author manuscript; available in PMC: 2015 Nov 1.
Published in final edited form as: Microvasc Res. 2014 Aug 15;0:10–15. doi: 10.1016/j.mvr.2014.07.016

Figure 1.

Figure 1

Differentiation of a lymphatic endothelial cell (LEC) from a venous endothelial cell (VEC) is driven by ERK activation, Sox18, Coup-TFII and Prox1. During this process, LECs gradually acquire specific gene signature.