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. Author manuscript; available in PMC: 2016 Jan 1.
Published in final edited form as: Biochim Biophys Acta. 2014 Nov 18;1852(1):166–174. doi: 10.1016/j.bbadis.2014.11.013

Figure 1. MALAT1 was up-regulated in human CRC tissues with metastasis.

Figure 1

(A) Semi-quantitative analyses of MALAT1 levels in human CRC tissues. MALAT1 expression was higher in CRCs (T) than adjacent normal tissues (N). The highest level of MALAT1 was observed in CRCs with lymph metastasis (L) in all groups. (B) MALAT1 expression in human CRC tissues was detected by real-time PCR and normalized to GAPDH. MALAT1 levels in all 9 groups (CRC, CRC with lymph metastasis (LymCRC), and adjacent normal tissues) were consistent with the semi-quantitative analyses shown in A. *P<0.05 compared to normal tissue group; **P<0.05 compared to CRC and normal tissue group. (C) MALAT1 expression in human CRCs with and without metastasis relative to match-normal tissues. The level of MALAT1 in human CRCs with metastasis (mCRC, n=9) was significantly higher than that in CRCs without metastasis (nmCRC, n=18).