TABLE 1.

Quantification of galectin-3 co-expression with tyrosinase and Tyrp-1

CELL TYPE	CELL AREA	CO-LOCALIZED PROTEINS	MANDER’S COEFFICIENT*
NHM	Cell body	Galectin-3 & Tyrp-1	0.945±0.04*1,
NHM	Cell body	Galectin-3 & tyrosinase	0.977±0.01
NHM	Cell body	Galectin-3 & RER	0.732±0.02*2
NHM	Cell body	Galectin-3 & nucleus	0.277+0.01*2
NHM	Entire cell	Galectin-3 & tyrosinase	0.856±0.038
HPS 1 (BLOC3)	Entire cell	“	0.647±0.116*3
HPS 2 (adaptin-3)	Entire cell	“	0.693±0.062*3
HPS 5 (BLOC2)	Entire cell	“	0.864±0.101

^*Mander’s Overlap coefficient ranges between 1 and zero with 1 being high-colocalisation and zero being low.

^*1Average plus standard deviation.

^*2P<0.05 compared to Galectin-3 & Tyrp-1 in Cell body of NHM

^*3P<0.05 compared to Galectin-3 & tyrosinase in Entire cell of NHM