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Collagen deposition (shown via Masson’s trichrome stain in blue above) by ADSCs delivered in a stiff fibrin composition (A) Symmetrical 6 mm full-thickness wounds were created on the backs of C57/B6 mice followed by no treatment (B and green arrow in A), administration of stiff formulation fibrin only containing no cells (C, and black arrow in A), or stiff fibrin formulation with 0.5 × 106 ADSCs (D). Significant granulation tissue and collagen deposition at day 5 of wound healing.
