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. Author manuscript; available in PMC: 2015 Dec 28.
Published in final edited form as: J Control Release. 2014 Oct 24;0:261–271. doi: 10.1016/j.jconrel.2014.10.019

Figure 10.

Figure 10

Estimated buildup of gluconic acid/gluconate buffer ([A]T,0) with time in Cell II of the oscillator prototype. Also shown are the estimated pKa values estimated at each time point. Estimations are based on curves in Fig. 9 fitted to Eq. (1). Average pKa=3.42 (black line). Cell I glucose concentration (75 mM) is shown as a red line.