. Author manuscript; available in PMC: 2015 Feb 15.

Published in final edited form as: J Immunol. 2014 Jan 10;192(4):1938–1945. doi: 10.4049/jimmunol.1302403

Table 1. Complementary models of fetal intervention in mice.

Models of Fetal Intervention	Rationale	% Resorption	# of litters (L)/# of fetuses (F)
Uninjected	Baseline	Syngeneic - 3.2±2 Allogeneic - 1.5± 1	7L/58F 12L/114F
PBS injection	Sterile inflammation	Syngeneic - 34±7 Allogeneic - 44±6^*	20L/155F 43L/355F
LPS injection	Strong inflammatory stimulus	Syngeneic - 90±6 Allogeneic - 79±4	10L/74F 32L/252F

χ² =0.04 between Syngeneic and Allogeneic matings undergoing fetal PBS injection;

χ²=NS between Syngeneic and Allogeneic matings in uninjected and LPS injected groups.

n≥4 independent experiments in each group.