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. Author manuscript; available in PMC: 2015 Jun 1.
Published in final edited form as: Curr Opin Struct Biol. 2014 Nov 25;0:112–121. doi: 10.1016/j.sbi.2014.10.006

Figure 1.

Figure 1

(a) The patellamide gene cluster contains genes patA to patG, coding for proteins PatA to PatG. The PatE protein contains: (1) a 37 residue leader and (2) two core peptides, which are processed to give patellamides C and A [11]. The core peptides are flanked at their N and C termini

(b) the final natural product patellamides C and A showing the chemical transformations during post-translational processing. The closely related patellin which is prenylated is shown

(c) the enzymes which tailor the core peptide. PatG encodes two functions and in addition has a DUF. PatA encodes the protease and also posses the same DUF.