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. 2014 Dec 1;24(10):570–578. doi: 10.1089/cap.2013.0135

FIG.1.

FIG.1.

Study design. Sequence 1: Multilayer extended-release bead methylphenidate (MPH-MLR) 80 mg capsule once daily (period 1); MPH-MLR 80 mg sprinkles once daily (period 2); and Ritalin® 25 mg three times daily (period 3). Sequence 2: Ritalin 25 mg three times daily (period 1); MPH-MLR 80 mg capsule once daily (period 2); and MPH-MLR 80 mg sprinkles once daily (period 3). Sequence 3: MPH-MLR 80 mg sprinkles once daily (period 1); Ritalin 25 mg three times daily (period 2); and MPH-MLR 80 mg capsule once daily (period 3). PK, pharmacokinetic.