Table 1.
Cytokines Tested in 45 Subjects Treated with Risperidone
| n=45 | Pretreatment Mean (SD) | Posttreatment Mean (SD) | p | rho (p) |
|---|---|---|---|---|
| TGF-β1 well 1 | 13040.2 (8885.9) | 16407.8 (1973.7) | 0.09 | 0.02 (0.91) |
| TGF-β2 well 2 | 11412.3 (8711.9) | 12794.0 (1485.6) | 0.27 | 0.07 (0.65) |
| BDNF | 1558.4 (292.0) | 1256.5 (129.5) | 0.86 | 0.03 (0.83) |
| Eotaxin | 81.9 (41.5) | 65.8 (30.2) | 0.0003* | −0.17 (0.27) |
| GCSF | 43.6 (75.1) | 43.8 (66.4) | 0.48 | −0.08 (0.63) |
| GMCSF | 84.7 (78.0) | 82.4 (11.7) | 0.60 | 0.02 (0.88) |
| IFN-α2 | 83.1 (202.3) | 75.1 (166.8) | 0.55 | −0.20 (0.20) |
| IFN-γ | 14.1 (20.8) | 12.5 (16.1) | 0.26 | −0.005(0.97) |
| IL-1α | 286.8 (256.4) | 292.6 (226.6) | 0.90 | 0.05 (0.76) |
| IL-1β | 2.9 (5.7) | 2.5 (4.3) | 0.17 | 0.02 (0.91) |
| IL-2 | 4.1 (12.5) | 2.9 (8.8) | 0.51 | 0.02 (0.91) |
| IL-5 | 2.5 (8.1) | 1.8 (4.3) | 0.73 | −0.001(0.95) |
| IL-6 | 5.9 (11.3) | 5.9 (12.7) | 0.31 | 0.25 (0.11) |
| IL-7 | 27.1 (59.4) | 25.8 (54.8) | 0.66 | −0.14 (0.35) |
| IL-8 | 10.3 (17.6) | 9.0 (14.2) | 0.36 | −0.01 (0.93) |
| IL-10 | 5.0 (4.4) | 5.3 (4.6) | 0.50 | 0.20 (0.21) |
| IL-12p40 | 84.4 (102.2) | 79.4 (93.5) | 0.08 | −0.17 (0.28) |
| IL-12p70 | 7.2 (12.0) | 5.2 (7.9) | 0.11 | 0.07 (0.66) |
| IL-13 | 3.0 (9.8) | 2.1 (6.7) | 0.08 | 0.16 (0.30) |
| IL-15 | 4.9 (11.6) | 4.8 (13.0) | 0.50 | −0.12 (0.46) |
| IL-17 | 10.4 (20.3) | 8.5 (15.9) | 0.19 | 0.10 (0.53) |
| IP-10 | 452.7 (413.2) | 444.8 (308.1) | 0.95 | 0.06 (0.72) |
| MCP-1 | 313.0 (143.0) | 265.7 (80.4) | 0.002* | 0.11 (0.48) |
| MIP-1α | 46.8 (46.5) | 44.0 (39.4) | 0.20 | 0.02 (0.92) |
| MIP-1β | 27.4 (27.3) | 25.8 (21.6) | 0.64 | 0.23 (0.15) |
| TNFα | 4.2 (1.6) | 4.0 (1.5) | 0.09 | 0.13 (0.42) |
| TNFβ | 6.9 (17.6) | 8.6 (25.4) | 0.39 | −0.01 (0.95) |
TGF, transforming growth factor; BDNF, brain-derived neurotrophic factor; GCSF, granulocyte colony-stimulating factor; GMCSF, granulocyte macrophage colony-stimulating factor; IFN, interferon; IL, interleukin; IP, Interferon gamma-induced protein; MCP, monocyte chemoattractant protein; MIP, macrophage inflammatory protein; TNF, tumor necrosis factor.