Figure 8. Release of microcrystal (1 mg)-adsorbed drugs at 37 °C against time.

(a) In 1.0 ml of water containing 1.0 equiv of hydrochloric acid relative to the molar amount of the Na⁺ ion of the attracted guests. (b) In 1.0 ml of CH₃CO₂H/CH₃CO₂Na (pH=4.5) buffer. The experiments were conducted with the samples being in the static state (blue triangles: Drug-3, black squares: Drug-1 and red circles: Drug-2) or on a shaking orbital shaker (green triangles: Drug-1 and purple triangles: Drug-2).