Table 1.

Dabigatran Dosing Recommendations

Indication	Creatinine clearance	Dose
Reduction in risk for stroke and systemic embolism in NVAF	>30 mL/min	150 mg orally twice daily
	15–30 mL/min	75 mg orally twice daily
	<15 mL/min or dialysis	Dosing recommendation cannot be provided
	30–50 mL/min + dronedarone or systemic ketoconazole	75 mg orally twice daily
	15–30 mL/min + dronedarone or systemic ketoconazole	Avoid use

NVAF indicates nonvalvular atrial fibrillation.

Used with permission from Pradaxa (dabigatran etexilate mesylate) capsules [prescribing information]. Ridgefield, CT: Boehringer Ingelheim Pharmaceuticals, Inc; September 2014.