. Author manuscript; available in PMC: 2014 Dec 17.

Published in final edited form as: Cochrane Database Syst Rev. 2013 Dec 3;12:CD005431. doi: 10.1002/14651858.CD005431.pub3

Table 6.

Risk of optic atrophy

Study	Test intervention	No. with outcome/No. in group	Control intervention	No. with outcome	Total No./No. with outcome
*Aminocaproic acid*
Crouch 1976	Oral aminocaproic acid	0/32	Placebo	2/27	2/59
Crouch 1997	Oral aminocaproic acid	0/29	Topical aminocaproic acid	0/35	0/64
*Tranexamic acid*
Varnek 1980	Tranexamic acid	1/102	Conservative treatment	0/130	1/232
*Cortisone*
Zetterstrom 1969	Atropine plus cortisone eyedrops	0/58	Conservative treatment	1/59	1/117
*Nondrug medical interventions*
Read 1974	Moderate ambulatory activity, patching and shielding of injured eye	NR	Bed rest with elevation of the head, bilateral patches and eye shield	NR	8/137

NR: not reported.