Skip to main content
. Author manuscript; available in PMC: 2015 Sep 10.
Published in final edited form as: Cell Host Microbe. 2014 Sep 10;16(3):412–418. doi: 10.1016/j.chom.2014.08.003

Figure 2. In Vivo Selection of R5-SHIVs.

Figure 2

(A and B) Plasma viral load in macaques inoculated with cocktails of SHIVs from Group 1 (A) or Group 2 (B). Animals were depleted of CD8+ cells at the time of and 1 week post inoculation. Red x indicates euthanasia due to AIDS. (C and D) Phylogenetic analysis of Env sequences found in the plasma of Group 1 (C) or Group 2 (D) SHIV-infected macaques. Black lines represent unmodified Env sequences from Group 1 or Group 2 viruses inoculated into animals and colored lines Env sequences obtained from infected animals at the indicated times p.i. Predominant Env sequences are labeled. See also Figure S2.