Table 1.
Formulation | Particle size (nm) | Polydispersity index | Zeta potential (mV) | Encapsulation efficiency (%) | Drug loading content (%) | CMC (mg/mL) | Factor Xa (%) |
---|---|---|---|---|---|---|---|
LHSA1 | 146.10±8.92 | 0.25±0.07 | −15.39±8.44 | – | – | ND | 60.41 |
LHSA3 | 175.60±6.54 | 0.23±0.08 | −33.92±1.34 | – | – | ND | 32.09 |
LHSA5 | 177.90±7.22 | 0.17±0.04 | −33.13±0.72 | – | – | 0.044 | 31.92 |
LHSA5/DCT (5:1, w/w) | 155.20±3.46 | 0.16±0.04 | −35.34±0.26 | 59.82±3.86 | 10.68±0.61 | – | 33.48 |
Notes:
Abbreviations: CMC, critical micelle concentration; ND, not determined.