Table 4.
Comparison of DRB3 allele frequencies within Pregsure© BVD vaccinated dams and BNP dams
| DRB3 allele frequencies | Non-BNP dams ( n = 21) | BNP dams ( n = 21) | P -value a | FDR-derived significance thresholds b |
|---|---|---|---|---|
| 1001 | 7 | 1 | 0.0574 | 0.004 |
| 14011 | 7 | 1 | 0.0574 | 0.008 |
| 2703 | 2 | 7 | 0.1555 | 0.013 |
| 0902 | 2 | 6 | 0.2646 | 0.017 |
| 1601 | 1 | 4 | 0.3597 | 0.021 |
| 0201 | 4 | 1 | 0.3597 | 0.025 |
| 0101 | 3 | 6 | 0.4827 | 0.029 |
| 0601 | 2 | 0 | 0.494 | 0.033 |
| 1101 | 9 | 11 | 0.7983 | 0.038 |
| 1201 | 3 | 4 | 1.000 | 0.042 |
| 0701 | 1 | 0 | 1.000 | 0.046 |
| UU01c | 1 | 1 | 1.000 | 0.050 |
aOrdered P-values from Fisher’s exact test.
bTo adjust for multiple comparisons the False Discovery Rate (FDR) was controlled at 5% using the principle from Benjamini and Hochberg [19]. The largest P-value lower than its FDR-derived significance threshold and all P-values smaller are significant.
cDenotes a local name and is not included in the IPD Bovine MHC class II database.