Table 2.
GO analysis of ankylosing spondylitis with different biological processes related to gene.
| Category | GO ID | Term | Count of genes | Percent of count of genes | Fold enrichment | P value |
|---|---|---|---|---|---|---|
| GOTERM_BP | GO:0002376 | Immune system process | 50 | 12.69 | 1.7 | 0.00016 |
| GOTERM_BP | GO:0002520 | Immune system development | 19 | 4.82 | 2.03 | 0.00285 |
| GOTERM_BP | GO:0003006 | Reproductive developmental process | 14 | 3.55 | 2.05 | 0.00898 |
| GOTERM_BP | GO:0006325 | Chromatin organization | 21 | 5.33 | 1.95 | 0.00276 |
| GOTERM_BP | GO:0006816 | Calcium ion transport | 13 | 3.3 | 2.71 | 0.00107 |
| GOTERM_BP | GO:0006950 | Response to stress | 64 | 16.24 | 1.35 | 0.00765 |
| GOTERM_BP | GO:0006996 | Organelle organization | 54 | 13.71 | 1.4 | 0.00669 |
| GOTERM_BP | GO:0007154 | Cell communication | 71 | 18.02 | 1.59 | 0.00005 |
| GOTERM_BP | GO:0007165 | Signal transduction | 108 | 27.41 | 1.24 | 0.00756 |
| GOTERM_BP | GO:0007242 | Intracellular signaling cascade | 73 | 18.53 | 1.7 | 0 |
| GOTERM_BP | GO:0007243 | Protein kinase cascade | 25 | 6.35 | 1.71 | 0.00663 |
| GOTERM_BP | GO:0007275 | Multicellular organismal development | 100 | 25.38 | 1.28 | 0.00422 |
| GOTERM_BP | GO:0009891 | Positive regulation of biosynthetic process | 37 | 9.39 | 2.02 | 0.00004 |
| GOTERM_BP | GO:0009893 | Positive regulation of metabolic process | 46 | 11.68 | 1.87 | 0.00003 |
| GOTERM_BP | GO:0009966 | Regulation of signal transduction | 46 | 11.68 | 1.85 | 0.00004 |
| GOTERM_BP | GO:0009967 | Positive regulation of signal transduction | 20 | 5.08 | 2.32 | 0.00044 |
| GOTERM_BP | GO:0010212 | Response to ionizing radiation | 6 | 1.52 | 3.8 | 0.0048 |
| GOTERM_BP | GO:0010557 | Positive regulation of macromolecule biosynthetic process | 34 | 8.63 | 1.98 | 0.00011 |
| GOTERM_BP | GO:0010604 | Positive regulation of macromolecule metabolic process | 44 | 11.17 | 1.92 | 0.00002 |
| GOTERM_BP | GO:0010627 | Regulation of protein kinase cascade | 15 | 3.81 | 2.07 | 0.00632 |
| GOTERM_BP | GO:0010628 | Positive regulation of gene expression | 32 | 8.12 | 2.11 | 0.00006 |
| GOTERM_BP | GO:0010646 | Regulation of cell communication | 50 | 12.69 | 1.75 | 0.00008 |
| GOTERM_BP | GO:0010647 | Positive regulation of cell communication | 21 | 5.33 | 2.25 | 0.00048 |
| GOTERM_BP | GO:0010740 | Positive regulation of protein kinase cascade | 13 | 3.3 | 2.55 | 0.00185 |
| GOTERM_BP | GO:0015674 | Di-, trivalent inorganic cation transport | 13 | 3.3 | 2.27 | 0.00501 |
| GOTERM_BP | GO:0016568 | Chromatin modification | 18 | 4.57 | 2.26 | 0.00114 |
| GOTERM_BP | GO:0018108 | Peptidyl-tyrosine phosphorylation | 9 | 2.28 | 3.21 | 0.00197 |
| GOTERM_BP | GO:0018212 | Peptidyl-tyrosine modification | 9 | 2.28 | 3.15 | 0.00225 |
Part of GO analysis of biological processes is supplied here; more data can be found in additional files.