Table 3.
GO analysis of differentially expressed genes associated with the cellular location and molecular function.
| Category | GO ID | Term | Count of genes | Percent of count of genes | Fold enrichment | P value |
|---|---|---|---|---|---|---|
| GOTERM_CC | GO:0000307 | Cyclin-dependent protein kinase Holoenzyme complex | 4 | 0.92 | 12.35 | 0.00022 |
| GOTERM_CC | GO:0005576 | Extracellular region | 82 | 18.76 | 1.52 | 0.00006 |
| GOTERM_CC | GO:0005615 | Extracellular space | 29 | 6.64 | 1.6 | 0.00908 |
| GOTERM_CC | GO:0005881 | Cytoplasmic microtubule | 3 | 0.69 | 6.95 | 0.00842 |
| GOTERM_CC | GO:0016324 | Apical plasma membrane | 10 | 2.29 | 2.39 | 0.00945 |
| GOTERM_CC | GO:0043005 | Neuron projection | 18 | 4.12 | 2 | 0.00423 |
| GOTERM_CC | GO:0044421 | Extracellular region part | 41 | 9.38 | 1.61 | 0.00181 |
| GOTERM_CC | GO:0045095 | Keratin filament | 8 | 1.83 | 3.29 | 0.00297 |
| GOTERM_MF | GO:0000287 | Magnesium ion binding | 22 | 5.2 | 1.73 | 0.009 |
| GOTERM_MF | GO:0004725 | Protein tyrosine phosphatase activity | 8 | 1.89 | 2.86 | 0.007 |
| GOTERM_MF | GO:0005057 | Receptor signaling protein activity | 11 | 2.6 | 2.51 | 0.0047 |
| GOTERM_MF | GO:0005102 | Receptor binding | 37 | 8.75 | 1.55 | 0.0055 |
| GOTERM_MF | GO:0005104 | Fibroblast growth factor receptor binding | 4 | 0.95 | 6.95 | 0.0023 |
| GOTERM_MF | GO:0005201 | Extracellular matrix structural constituent | 7 | 1.65 | 3.04 | 0.0082 |
| GOTERM_MF | GO:0005262 | Calcium channel activity | 7 | 1.65 | 3.32 | 0.0051 |
| GOTERM_MF | GO:0008083 | Growth factor activity | 12 | 2.84 | 2.72 | 0.0016 |
| GOTERM_MF | GO:0008138 | Protein tyrosine/serine/threonine phosphatase activity | 6 | 1.42 | 4.86 | 0.0014 |
| GOTERM_MF | GO:0008168 | Methyltransferase activity | 11 | 2.6 | 2.27 | 0.0097 |
| GOTERM_MF | GO:0008276 | Protein methyltransferase activity | 6 | 1.42 | 3.77 | 0.005 |
| GOTERM_MF | GO:0042054 | Histone methyltransferase activity | 5 | 1.18 | 4.05 | 0.0075 |