Network activity and PC dendrite growth on hybrid matrix. (A) Representative micrographs of 16 days old PCs on hybrid matrix (collagen 1.8 mg/mL, PA 1 mg/mL) without any pharmacological treatment (control, left image) and in presence of tetrodotoxin (TTX 1 μM, middle image) or cyclothiazide (CTZ 20 μM, right image). (B) Quantification of PC dendrite morphology following exposure to TTX and CTZ [*:p<0.05, **:p<0.01, ***:p<0.001; n>100 PCs].