Table 3.

Association of Clinical Severity in 1,401 AMD Cases with Genotypes at CFH, ARMS2, C3, and CFB Polymorphisms

	Grade 3, N = 398	Grade 4, N = 173	Grade 5, N = 830	P
	Frequency	Frequency	Frequency
CFH Y402H				0.91
CC	0.34	0.36	0.35
CT	0.47	0.48	0.48
TT	0.19	0.16	0.17
ARMS2 A69S				8.2 × 10⁻¹¹
GG	0.50	0.41	0.30
GT	0.40	0.39	0.45
TT	0.10	0.20	0.25
C3 R102G				0.61
GG	0.55	0.51	0.53
GC	0.37	0.37	0.39
CC	0.08	0.12	0.09
CFB R32Q				0.48
GG	0.91	0.90	0.91
GA	0.09	0.10	0.08
AA	0	0	0.01