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. Author manuscript; available in PMC: 2014 Dec 17.
Published in final edited form as: Cochrane Database Syst Rev. 2012 Apr 18;4:CD001430. doi: 10.1002/14651858.CD001430.pub3

Comparison 1. Total intravenous corticosteroid dose more than or equal to 3000 mg.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Participants with normal visual acuity at 6 months 2 346 Risk Ratio (M-H, Fixed, 95% CI) 1.06 [0.89, 1.27]
2 Participants with normal visual acuity at 1 year 1 270 Risk Ratio (M-H, Fixed, 95% CI) 1.06 [0.92, 1.22]
3 Participants with normal visual acuity at 1 month 1 285 Risk Ratio (M-H, Fixed, 95% CI) 1.08 [0.89, 1.31]
4 Participants with normal contrast sensitivity at 6 months 2 346 Risk Ratio (M-H, Fixed, 95% CI) 1.10 [0.92, 1.32]
5 Participants with normal contrast sensitivity at 1 year 2 Risk Ratio (M-H, Fixed, 95% CI) Subtotals only
6 Participants with normal contrast sensitivity at 1 month 2 322 Risk Ratio (M-H, Random, 95% CI) 1.27 [0.74, 2.16]
7 Participants with normal visual field at 6 months 2 346 Risk Ratio (M-H, Fixed, 95% CI) 1.08 [0.96, 1.22]
8 Participants with normal visual field at 1 year 2 316 Risk Ratio (M-H, Fixed, 95% CI) 1.02 [0.86, 1.20]
9 Participants with normal visual field at 1 month 2 330 Risk Ratio (M-H, Fixed, 95% CI) 1.43 [1.12, 1.84]