Table 2.

Canine cell lines.

Cell Line/Reference	Derived From	Phenotype	Notable Features
GL-1 (107, 124, 147)	B-cell leukemia	IgH+, CD79a+, CD3−	FLT3 ITD
UL-1 (132)	ascites from renal lymphoma patient	TCR+, IgH−, CD3−, CD21−
CL-1 (124, 148)	pleural fluid from T-cell lymphoma patient	TCR+, IgH−, CD3−, CD21−	homozygous PTEN deletion
CLBL-1 (149)	FNA from B-cell lymphoma patient	TCR−, IgH+, CD79a+, CD3−
Nody-1 (132)	ascites from alimentary lymphoma patient	TCR+, IgH−, CD3+, CD21−	KIT overexpression, also called TL-1
Ema (132)	pleural fluid from T-cell lymphoma patient	TCR+, IgH−, CD3+, CD21−
CLK (132)	ascites from T-cell lymphoma patient	TCR+, IgH−, CD3−, CD21−
CLC (132)	pleural fluid from T-cell lymphoma patient	TCR−, IgH−, CD3−, CD21−
3132 (150, 151)	ascites from malignant lymphoma patient	IgH+	produces retroviral particles?
CLGL-90 (124, 152)	LGL T-cell leukemia	TCR+, CD3+, CD79a−	homozygous CDKN2A deletion
17–71 (124, 152, 153)	lymph node from B-cell lymphoma patient	TCR−, CD79a+, CD3−, CD21−	near tetraploid
OSW (130)	pleural fluid from T-cell lymphoma patient	TCR+, IgH−, CD3−, CD21−	MYC amplification; PTEN, p16, and RB1 deletion
CLL-1390 (124, 152)	primitive T-cell leukemia	TCR+, CD34+, CD3−, CD21−	homozygous PTEN deletion
DLC 01 (128)	lymph node from a Sezary syndrome patient	CD3+, CD4−, CD8+	produces retroviral particles?
DLC 02 (128)	peripheral blood lymphocytes from an LGL patient	CD4−, CD8+	produces retroviral particles?

LGL: large granulocytic leukemia