Fig. 5.

Peptide inhibition of PKA. Phosphorylation of the PKA substrate Kemptide peptide was determined by incubation with 2.5 nM recombinant mouse PKA catalytic subunit in the absence (Ctrl) or presence of peptide inhibitors (concentrations ranging from 1 to 100 μM) as described in “Materials and Methods” section. Data shown are the mean ± SEM for four or more experiments performed in duplicate and normalized to the % of control