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. Author manuscript; available in PMC: 2014 Dec 17.
Published in final edited form as: Nat Rev Nephrol. 2014 Jul 1;10(9):504–516. doi: 10.1038/nrneph.2014.112

Figure 1.

Figure 1

Stages of skeletal muscle regeneration. Specific biomarkers can be detected at each stage of myogenesis. Satellite cells are normally quiescent, but when stimulated by factors such as insulin-like growth factor 1, they express myogenic regulatory factors, including myoblast determination protein 1. Expression of these factors leads to proliferation and differentiation of satellite cells into myoblasts and myocytes that can fuse to form myotubes or myofibrils. Abbreviations: Myf, myogenic factor; Pax, paired box protein.