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. Author manuscript; available in PMC: 2015 May 18.
Published in final edited form as: Nat Commun. 2014 Nov 18;5:5460. doi: 10.1038/ncomms6460

Figure 3. Redox-sensitive dual-modality imaging mechanism.

Figure 3

(a) Schematic for dual-modality molecular imaging in response to nitroxide reduction. (b) Emission behaviour of OF1 and a control polymer with Cy5.5 and no nitroxides upon exposure to varied amounts of ascorbate or glutathione (GSH) in PBS buffer. The solution pH before and after addition of 60 equiv. ascorbic acid was 7.0 and 6.31, respectively; this pH change has no affect on Cy5.5 absorbance/emission. equiv., equivalent.