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. 2014 Dec 17;9(12):e114552. doi: 10.1371/journal.pone.0114552

Figure 1. Results of the genome-wide association study.

Figure 1

Genome-wide association analysis identifies the retinopathy locus in the SV breed. A) Manhattan plot with tentative association on CFA17 (praw = 7.7×10−5), replication analysis supported the association (prepl = 2.7×10−5) and was confirmed by combined analysis (p = 4.3×10−8). CFA39 represent the X chromosome. B) A close-up of the associated region on CFA17, which spans from 38.16 Mb to 43.64 Mb. C) The associated region harbors over hundred genes, including a known PRA gene, MERTK.