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. 2014 Dec 17;9(12):e115283. doi: 10.1371/journal.pone.0115283

Figure 3. Exposure to BDS decreases rRNA levels and increases DNA methylation at the rDNA promoter of 14-day old pups.

Figure 3

Exposure to BDS decreases total amount of DNA (A) and RNA (B) harvested from the hippocampus of 14-day old pups. C. Relative levels of rRNA are lower in BDS compared to control 14-d old pups. Exposure to BDS increases DNA methylation at CG_6 (D and E). Unpaired Student t tests (A, B, C, E), Repeated measures ANOVA followed by simple-effect analysis (D). Error bars represent mean ± SEM, *p<0.05.