Skip to main content
. 2014 Dec 17;9(12):e115406. doi: 10.1371/journal.pone.0115406

Figure 1. Family data collection, cataract phenotype, and mutation sequencing of Cx50.

Figure 1

A: Pedigree of the proband. The black symbols indicate the affected individuals. The arrow indicates the proband. All the living members shown in this figure participated in this project. B: Diffuse illumination of the left eye of the proband (the arrows show transparent anterior suture). C: Slit lamp photograph of the lens of the proband showing the nuclear opacities; anterior and posterior sutures are not involved (arrowheads). D: Partial DNA sequence of GJA8 from one normal individual and one affected individual. The black box shows a heterozygous mutation (c.131T>C) in exon 2. E: Conservation analysis of p.V44A of the Cx50 gene.