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Illustration of local shape differences (P values) between the heterozygous APOE e4 carriers (e3/e4, N = 189) and the homozygous APOE e4 carriers (e4/e4, N = 47) in the nondemented cohort. Nonblue colors show vertices with statistical differences, at the nomial 0.05 level, uncorrected. The overall significance after multiple comparisons with permutation test is P < 0.142. [Color figure can be viewed in the online issue, which is available at http://wileyonlinelibrary.com.]
